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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Red Ruffing# | 246 | 1924-1946 | |
| 2 | Ted Lyons# | 225 | 1923-1946 | |
| 3 | Bobo Newsom# | 187 | 1929-1946 | |
| 4 | Tommy Bridges# | 176 | 1930-1946 | |
| 5 | Mel Harder# | 154 | 1928-1945 | |
| 6 | Curt Davis# | 142 | 1934-1946 | |
| 7 | Hal Schumacher# | 140 | 1931-1946 | |
| 8 | Jack Knott# | 139 | 1933-1942 | |
| 9 | Bill Lee# | 132 | 1934-1946 | |
| 10 | Bill Dietrich# | 126 | 1933-1946 | |
| 10 | Bucky Walters# | 126 | 1931-1946 | |
| 12 | George Caster# | 120 | 1934-1946 | |
| 13 | Thornton Lee# | 116 | 1933-1946 | |
| 14 | Schoolboy Rowe# | 106 | 1933-1946 | |
| 15 | Si Johnson# | 104 | 1928-1943 | |
| 15 | Dutch Leonard# | 104 | 1933-1946 | |
| 17 | Claude Passeau# | 97 | 1935-1946 | |
| 18 | Nels Potter# | 96 | 1936-1946 | |
| 18 | Eddie Smith# | 96 | 1936-1946 | |
| 20 | Harry Gumbert# | 95 | 1935-1944 | |
| 21 | Johnny Rigney# | 84 | 1937-1946 | |
| 22 | Rip Sewell# | 82 | 1932-1946 | |
| 23 | Jim Bagby# | 80 | 1938-1945 | |
| 24 | Denny Galehouse# | 76 | 1934-1946 | |
| 25 | Tiny Bonham# | 72 | 1940-1946 | |
| 26 | Al Benton# | 70 | 1934-1946 | |
| 26 | Fritz Ostermueller# | 70 | 1934-1946 | |
| 28 | Bob Muncrief# | 67 | 1937-1946 | |
| 29 | Bob Feller# | 65 | 1936-1946 | |
| 29 | Hugh Mulcahy# | 65 | 1935-1945 | |
| 31 | Mort Cooper# | 64 | 1938-1946 | |
| 31 | Kirby Higbe# | 64 | 1937-1946 | |
| 33 | Johnny Niggeling# | 63 | 1938-1946 | |
| 33 | Clyde Shoun# | 63 | 1935-1946 | |
| 35 | Spud Chandler# | 57 | 1937-1946 | |
| 36 | Dizzy Trout# | 56 | 1939-1946 | |
| 37 | Lum Harris# | 55 | 1941-1944 | |
| 38 | Johnny Lanning# | 52 | 1936-1945 | |
| 39 | Johnny Humphries# | 50 | 1938-1946 | |
| 39 | Steve Sundra# | 50 | 1936-1944 | |
| 39 | Bill Voiselle# | 50 | 1942-1946 | |
| 42 | Harry Feldman# | 49 | 1941-1946 | |
| 42 | Ed Heusser# | 49 | 1935-1946 | |
| 44 | Johnny Murphy# | 47 | 1932-1943 | |
| 45 | Al Hollingsworth# | 46 | 1935-1946 | |
| 45 | Tex Hughson# | 46 | 1941-1946 | |
| 45 | Mike Ryba# | 46 | 1935-1946 | |
| 48 | Johnny Vander Meer# | 45 | 1937-1946 | |
| 48 | Roger Wolff# | 45 | 1941-1946 | |
| 50 | Red Barrett# | 44 | 1937-1946 | |
| 50 | Al Javery# | 44 | 1940-1945 | |
| 50 | Bill Posedel# | 44 | 1938-1941 | |
| 53 | Jack Kramer# | 43 | 1939-1946 | |
| 54 | Hank Borowy# | 42 | 1942-1946 | |
| 54 | Mace Brown# | 42 | 1935-1943 | |
| 54 | Al Milnar# | 42 | 1936-1943 | |
| 57 | Sid Hudson# | 41 | 1940-1942 | |
| 58 | Hugh Casey# | 40 | 1935-1946 | |
| 58 | Bob Klinger# | 40 | 1938-1943 | |
| 58 | Hal Newhouser# | 40 | 1939-1946 | |
| 58 | Ike Pearson# | 40 | 1939-1942 | |
| 58 | Marius Russo# | 40 | 1939-1943 | |
| 63 | Joe Dobson# | 39 | 1939-1946 | |
| 64 | Jake Wade# | 38 | 1936-1946 | |
| 65 | Joe Haynes# | 37 | 1939-1946 | |
| 66 | Nate Andrews# | 36 | 1937-1945 | |
| 66 | Earl Caldwell# | 36 | 1928-1946 | |
| 66 | Orval Grove# | 36 | 1940-1946 | |
| 66 | Art Herring# | 36 | 1929-1945 | |
| 66 | Nick Strincevich# | 36 | 1940-1946 | |
| 71 | Johnny Hutchings# | 35 | 1940-1945 | |
| 72 | Johnny Gorsica# | 34 | 1940-1944 | |
| 73 | Phil Marchildon# | 33 | 1940-1946 | |
| 74 | Charlie Wagner# | 32 | 1938-1942 | |
| 74 | Hank Wyse# | 32 | 1942-1946 | |
| 76 | Bob Carpenter# | 30 | 1940-1942 | |
| 77 | Jesse Flores# | 29 | 1942-1946 | |
| 78 | Joe Krakauskas# | 28 | 1937-1946 | |
| 78 | Early Wynn# | 28 | 1939-1946 | |
| 80 | Russ Christopher# | 27 | 1942-1946 | |
| 80 | Junior Thompson# | 27 | 1939-1942 | |
| 80 | Ernie White# | 27 | 1940-1946 | |
| 83 | Harry Brecheen# | 26 | 1940-1946 | |
| 83 | Ken Heintzelman# | 26 | 1937-1942 | |
| 83 | Ken Raffensberger# | 26 | 1939-1946 | |
| 86 | Bill Fleming# | 25 | 1940-1944 | |
| 86 | Hal Gregg# | 25 | 1943-1946 | |
| 86 | Mickey Haefner# | 25 | 1943-1946 | |
| 86 | Bill Zuber# | 25 | 1936-1945 | |
| 90 | Ace Adams# | 24 | 1941-1945 | |
| 90 | Herman Besse# | 24 | 1940-1946 | |
| 90 | Al Gerheauser# | 24 | 1943-1946 | |
| 93 | Fred Hutchinson# | 23 | 1939-1946 | |
| 93 | Johnny Podgajny# | 23 | 1940-1946 | |
| 93 | Preacher Roe# | 23 | 1938-1946 | |
| 96 | Jack Brewer# | 22 | 1944-1945 | |
| 96 | Ed Head# | 22 | 1940-1946 | |
| 96 | Ed Lopat# | 22 | 1944-1946 | |
| 99 | Bill Bevens# | 21 | 1944-1946 | |
| 99 | Tommy Hughes# | 21 | 1941-1946 |
