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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Red Ruffing# | 1957 | 1924-1945 | |
| 2 | Bobo Newsom# | 1834 | 1929-1946 | |
| 3 | Tommy Bridges# | 1658 | 1930-1946 | |
| 4 | Bob Feller# | 1299 | 1936-1946 | |
| 5 | Mel Harder# | 1122 | 1928-1945 | |
| 6 | Ted Lyons# | 1065 | 1923-1946 | |
| 7 | Claude Passeau# | 1034 | 1935-1946 | |
| 8 | Bucky Walters# | 987 | 1931-1946 | |
| 9 | Bill Lee# | 957 | 1934-1945 | |
| 10 | Johnny Vander Meer# | 885 | 1937-1946 | |
| 11 | Hal Schumacher# | 858 | 1931-1942 | |
| 12 | Hal Newhouser# | 853 | 1939-1946 | |
| 13 | Thornton Lee# | 847 | 1933-1946 | |
| 14 | Mort Cooper# | 804 | 1938-1946 | |
| 15 | Si Johnson# | 770 | 1928-1943 | |
| 16 | Schoolboy Rowe# | 722 | 1933-1946 | |
| 17 | Dutch Leonard# | 710 | 1933-1946 | |
| 18 | Curt Davis# | 684 | 1934-1945 | |
| 19 | Denny Galehouse# | 676 | 1934-1946 | |
| 20 | Dizzy Trout# | 671 | 1939-1946 | |
| 21 | Bill Dietrich# | 617 | 1933-1945 | |
| 22 | Fritz Ostermueller# | 610 | 1934-1946 | |
| 23 | Eddie Smith# | 608 | 1936-1943 | |
| 24 | Johnny Niggeling# | 589 | 1938-1946 | |
| 25 | Al Hollingsworth# | 583 | 1935-1945 | |
| 26 | Kirby Higbe# | 582 | 1937-1943 | |
| 27 | Harry Gumbert# | 580 | 1935-1944 | |
| 28 | George Caster# | 576 | 1934-1945 | |
| 29 | Max Lanier# | 551 | 1938-1946 | |
| 30 | Johnny Rigney# | 538 | 1937-1946 | |
| 31 | Rip Sewell# | 505 | 1932-1946 | |
| 32 | Al Benton# | 504 | 1934-1946 | |
| 33 | Nels Potter# | 491 | 1936-1946 | |
| 34 | Jack Knott# | 482 | 1933-1942 | |
| 35 | Al Javery# | 470 | 1940-1945 | |
| 36 | Mace Brown# | 425 | 1935-1943 | |
| 37 | Spud Chandler# | 414 | 1937-1946 | |
| 38 | Clyde Shoun# | 400 | 1935-1944 | |
| 39 | Jim Bagby# | 392 | 1938-1945 | |
| 39 | Hank Borowy# | 392 | 1942-1946 | |
| 41 | Roger Wolff# | 370 | 1941-1946 | |
| 42 | Tex Hughson# | 367 | 1941-1946 | |
| 43 | Johnny Murphy# | 350 | 1932-1943 | |
| 44 | Al Milnar# | 349 | 1936-1943 | |
| 44 | Allie Reynolds# | 349 | 1942-1945 | |
| 46 | Bob Muncrief# | 333 | 1937-1946 | |
| 47 | Jack Kramer# | 332 | 1939-1946 | |
| 48 | Bob Klinger# | 329 | 1938-1943 | |
| 49 | Bill Zuber# | 328 | 1936-1945 | |
| 50 | Joe Krakauskas# | 327 | 1937-1946 | |
| 51 | Tiny Bonham# | 320 | 1940-1946 | |
| 52 | Rube Melton# | 318 | 1941-1944 | |
| 53 | Johnny Humphries# | 307 | 1938-1945 | |
| 54 | Marius Russo# | 304 | 1939-1943 | |
| 55 | Russ Christopher# | 302 | 1942-1946 | |
| 55 | Mike Ryba# | 302 | 1935-1946 | |
| 57 | Hugh Mulcahy# | 300 | 1935-1945 | |
| 57 | Bill Voiselle# | 300 | 1942-1946 | |
| 59 | Joe Dobson# | 293 | 1939-1946 | |
| 60 | Johnny Lanning# | 279 | 1936-1945 | |
| 61 | Russ Bauers# | 278 | 1936-1946 | |
| 62 | Sid Hudson# | 276 | 1940-1942 | |
| 63 | Paul Erickson# | 273 | 1941-1946 | |
| 64 | Junior Thompson# | 271 | 1939-1942 | |
| 65 | Orval Grove# | 262 | 1940-1946 | |
| 66 | Hugh Casey# | 257 | 1935-1942 | |
| 67 | Joe Haynes# | 255 | 1939-1945 | |
| 68 | Steve Gromek# | 254 | 1941-1946 | |
| 69 | Harry Feldman# | 251 | 1941-1945 | |
| 70 | Hal Gregg# | 245 | 1943-1946 | |
| 71 | Preacher Roe# | 241 | 1938-1946 | |
| 72 | Jake Wade# | 240 | 1936-1946 | |
| 73 | Johnny Gorsica# | 238 | 1940-1944 | |
| 74 | Jesse Flores# | 237 | 1942-1946 | |
| 75 | Mickey Haefner# | 235 | 1943-1946 | |
| 76 | Ed Heusser# | 232 | 1935-1946 | |
| 76 | Early Wynn# | 232 | 1939-1946 | |
| 78 | Ernie White# | 227 | 1940-1946 | |
| 79 | Harry Brecheen# | 226 | 1940-1946 | |
| 80 | Virgil Trucks# | 221 | 1941-1946 | |
| 81 | Bill Posedel# | 218 | 1938-1941 | |
| 82 | Hank Wyse# | 217 | 1942-1946 | |
| 83 | Ken Heintzelman# | 214 | 1937-1942 | |
| 84 | Al Gerheauser# | 213 | 1943-1945 | |
| 84 | Steve Sundra# | 213 | 1936-1944 | |
| 86 | Johnny Hutchings# | 211 | 1940-1945 | |
| 87 | Ken Raffensberger# | 207 | 1939-1946 | |
| 88 | Red Barrett# | 203 | 1937-1946 | |
| 88 | Art Herring# | 203 | 1929-1945 | |
| 90 | Nate Andrews# | 198 | 1937-1945 | |
| 90 | Nick Strincevich# | 198 | 1940-1945 | |
| 92 | Lum Harris# | 197 | 1941-1944 | |
| 92 | Walt Masterson# | 197 | 1939-1945 | |
| 94 | Vern Olsen# | 195 | 1939-1946 | |
| 95 | Ed Head# | 192 | 1940-1946 | |
| 96 | Don Black# | 190 | 1943-1945 | |
| 96 | Phil Marchildon# | 190 | 1940-1945 | |
| 98 | Oscar Judd# | 178 | 1941-1945 | |
| 99 | Ace Adams# | 168 | 1941-1945 | |
| 100 | Bill Fleming# | 157 | 1940-1944 |
