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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Red Ruffing# | 1967 | 1924-1946 | |
| 2 | Bobo Newsom# | 1876 | 1929-1946 | |
| 3 | Tommy Bridges# | 1660 | 1930-1946 | |
| 4 | Bob Feller# | 1365 | 1936-1946 | |
| 5 | Mel Harder# | 1122 | 1928-1945 | |
| 6 | Ted Lyons# | 1078 | 1923-1946 | |
| 7 | Claude Passeau# | 1066 | 1935-1946 | |
| 8 | Bucky Walters# | 1004 | 1931-1946 | |
| 9 | Bill Lee# | 965 | 1934-1946 | |
| 10 | Hal Newhouser# | 927 | 1939-1946 | |
| 11 | Johnny Vander Meer# | 920 | 1937-1946 | |
| 12 | Thornton Lee# | 884 | 1933-1946 | |
| 13 | Hal Schumacher# | 880 | 1931-1946 | |
| 14 | Mort Cooper# | 830 | 1938-1946 | |
| 15 | Si Johnson# | 770 | 1928-1943 | |
| 16 | Schoolboy Rowe# | 750 | 1933-1946 | |
| 17 | Dutch Leonard# | 743 | 1933-1946 | |
| 18 | Dizzy Trout# | 717 | 1939-1946 | |
| 19 | Denny Galehouse# | 705 | 1934-1946 | |
| 20 | Curt Davis# | 689 | 1934-1946 | |
| 21 | Bill Dietrich# | 636 | 1933-1946 | |
| 22 | Fritz Ostermueller# | 634 | 1934-1946 | |
| 23 | Eddie Smith# | 626 | 1936-1946 | |
| 24 | Johnny Niggeling# | 619 | 1938-1946 | |
| 25 | Max Lanier# | 612 | 1938-1946 | |
| 26 | Kirby Higbe# | 604 | 1937-1946 | |
| 27 | Al Hollingsworth# | 590 | 1935-1946 | |
| 28 | George Caster# | 589 | 1934-1946 | |
| 29 | Harry Gumbert# | 580 | 1935-1944 | |
| 30 | Johnny Rigney# | 564 | 1937-1946 | |
| 31 | Nels Potter# | 535 | 1936-1946 | |
| 32 | Al Benton# | 527 | 1934-1946 | |
| 33 | Rip Sewell# | 508 | 1932-1946 | |
| 34 | Jack Knott# | 482 | 1933-1942 | |
| 35 | Al Javery# | 470 | 1940-1945 | |
| 36 | Spud Chandler# | 454 | 1937-1946 | |
| 37 | Tex Hughson# | 430 | 1941-1946 | |
| 38 | Mace Brown# | 425 | 1935-1943 | |
| 39 | Hank Borowy# | 424 | 1942-1946 | |
| 40 | Clyde Shoun# | 400 | 1935-1946 | |
| 41 | Roger Wolff# | 397 | 1941-1946 | |
| 42 | Jim Bagby# | 392 | 1938-1945 | |
| 43 | Allie Reynolds# | 373 | 1942-1946 | |
| 44 | Bob Muncrief# | 355 | 1937-1946 | |
| 45 | Johnny Murphy# | 350 | 1932-1943 | |
| 46 | Jack Kramer# | 349 | 1939-1946 | |
| 46 | Al Milnar# | 349 | 1936-1943 | |
| 48 | Tiny Bonham# | 342 | 1940-1946 | |
| 49 | Joe Krakauskas# | 339 | 1937-1946 | |
| 50 | Joe Dobson# | 331 | 1939-1946 | |
| 51 | Bob Klinger# | 329 | 1938-1943 | |
| 52 | Bill Zuber# | 328 | 1936-1945 | |
| 53 | Rube Melton# | 322 | 1941-1946 | |
| 54 | Russ Christopher# | 313 | 1942-1946 | |
| 55 | Mike Ryba# | 311 | 1935-1946 | |
| 56 | Johnny Humphries# | 310 | 1938-1946 | |
| 57 | Bill Voiselle# | 307 | 1942-1946 | |
| 58 | Marius Russo# | 304 | 1939-1943 | |
| 59 | Hugh Mulcahy# | 300 | 1935-1945 | |
| 60 | Russ Bauers# | 290 | 1936-1946 | |
| 61 | Virgil Trucks# | 285 | 1941-1946 | |
| 62 | Joe Haynes# | 281 | 1939-1946 | |
| 63 | Johnny Lanning# | 279 | 1936-1945 | |
| 64 | Paul Erickson# | 276 | 1941-1946 | |
| 64 | Sid Hudson# | 276 | 1940-1942 | |
| 66 | Harry Feldman# | 275 | 1941-1946 | |
| 66 | Hal Gregg# | 275 | 1943-1946 | |
| 68 | Preacher Roe# | 274 | 1938-1946 | |
| 69 | Steve Gromek# | 272 | 1941-1946 | |
| 70 | Junior Thompson# | 271 | 1939-1942 | |
| 71 | Orval Grove# | 269 | 1940-1946 | |
| 72 | Hugh Casey# | 268 | 1935-1946 | |
| 73 | Harry Brecheen# | 267 | 1940-1946 | |
| 74 | Mickey Haefner# | 259 | 1943-1946 | |
| 75 | Jesse Flores# | 255 | 1942-1946 | |
| 76 | Jake Wade# | 249 | 1936-1946 | |
| 77 | Ed Heusser# | 248 | 1935-1946 | |
| 78 | Early Wynn# | 247 | 1939-1946 | |
| 79 | Walt Masterson# | 239 | 1939-1946 | |
| 80 | Johnny Gorsica# | 238 | 1940-1944 | |
| 81 | Hank Wyse# | 230 | 1942-1946 | |
| 82 | Ken Raffensberger# | 228 | 1939-1946 | |
| 83 | Ernie White# | 227 | 1940-1946 | |
| 84 | Al Gerheauser# | 224 | 1943-1946 | |
| 85 | Phil Marchildon# | 219 | 1940-1946 | |
| 86 | Bill Posedel# | 218 | 1938-1941 | |
| 87 | Red Barrett# | 215 | 1937-1946 | |
| 88 | Ken Heintzelman# | 214 | 1937-1942 | |
| 89 | Steve Sundra# | 213 | 1936-1944 | |
| 90 | Johnny Hutchings# | 211 | 1940-1945 | |
| 91 | Nick Strincevich# | 207 | 1940-1946 | |
| 92 | Art Herring# | 203 | 1929-1945 | |
| 93 | Vern Olsen# | 201 | 1939-1946 | |
| 94 | Nate Andrews# | 198 | 1937-1945 | |
| 94 | Ed Head# | 198 | 1940-1946 | |
| 96 | Lum Harris# | 197 | 1941-1944 | |
| 97 | Mickey Harris# | 195 | 1940-1946 | |
| 97 | Oscar Judd# | 195 | 1941-1946 | |
| 99 | Don Black# | 190 | 1943-1945 | |
| 100 | Ed Lopat# | 186 | 1944-1946 |
