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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Joe Medwick# | 197 | 1932-1946 | |
| 2 | Charlie Keller# | 100 | 1939-1946 | |
| 3 | Jeff Heath# | 98 | 1936-1946 | |
| 4 | Ted Williams# | 96 | 1939-1946 | |
| 5 | Augie Galan# | 58 | 1934-1946 | |
| 6 | Hank Greenberg# | 56 | 1930-1946 | |
| 7 | Danny Litwhiler# | 54 | 1940-1946 | |
| 8 | Joe DiMaggio# | 29 | 1936-1946 | |
| 9 | Chet Laabs# | 26 | 1937-1946 | |
| 10 | Ben Chapman# | 24 | 1930-1945 | |
| 10 | Jim Russell# | 24 | 1942-1946 | |
| 12 | Morrie Arnovich# | 22 | 1936-1941 | |
| 12 | Max West# | 22 | 1938-1946 | |
| 14 | Roy Cullenbine# | 21 | 1938-1946 | |
| 15 | Dick Wakefield# | 20 | 1941-1946 | |
| 16 | Maurice Van Robays# | 18 | 1939-1946 | |
| 17 | Sam Chapman# | 17 | 1938-1946 | |
| 18 | Dom Dallessandro# | 16 | 1937-1946 | |
| 18 | Pat Seerey# | 16 | 1943-1946 | |
| 20 | Lou Novikoff# | 15 | 1941-1944 | |
| 21 | Buster Mills# | 12 | 1934-1942 | |
| 22 | Willard Marshall# | 11 | 1942-1946 | |
| 23 | George Case# | 10 | 1937-1946 | |
| 23 | Stan Musial# | 10 | 1941-1946 | |
| 25 | Tommy Henrich# | 8 | 1937-1946 | |
| 26 | Peanuts Lowrey# | 7 | 1942-1946 | |
| 26 | Barney McCosky# | 7 | 1939-1946 | |
| 28 | Ford Garrison# | 6 | 1943-1945 | |
| 28 | Johnny Hopp# | 6 | 1939-1946 | |
| 28 | Dixie Walker# | 6 | 1931-1946 | |
| 28 | Al Zarilla# | 6 | 1943-1946 | |
| 32 | Guy Curtright# | 5 | 1943-1946 | |
| 32 | Mike McCormick# | 5 | 1940-1946 | |
| 32 | Don Padgett# | 5 | 1937-1941 | |
| 32 | Tuck Stainback# | 5 | 1934-1946 | |
| 36 | Russ Derry# | 4 | 1944-1946 | |
| 36 | Frank Secory# | 4 | 1940-1945 | |
| 38 | Glenn McQuillen# | 3 | 1938-1942 | |
| 38 | Jimmy Outlaw# | 3 | 1937-1945 | |
| 38 | Jimmy Wasdell# | 3 | 1937-1946 | |
| 41 | Lou Finney# | 2 | 1931-1946 | |
| 41 | Babe Martin# | 2 | 1944-1945 | |
| 41 | Stan Spence# | 2 | 1940-1946 | |
| 41 | Elmer Valo# | 2 | 1940-1946 | |
| 45 | Del Ennis# | 1 | 1946-1946 | |
| 45 | Ned Harris# | 1 | 1941-1943 | |
| 45 | Red Schoendienst# | 1 | 1945-1946 | |
| 45 | Clyde Vollmer# | 1 | 1942-1942 | |
| 45 | Roy Weatherly# | 1 | 1936-1943 | |
| 50 | George Binks# | 0 | 1944-1946 | |
| 50 | Gil Coan# | 0 | 1946-1946 | |
| 50 | Doc Cramer# | 0 | 1929-1946 | |
| 50 | Vince DiMaggio# | 0 | 1937-1945 | |
| 50 | Erv Dusak# | 0 | 1941-1946 | |
| 50 | Charlie Gilbert# | 0 | 1940-1946 | |
| 50 | Carden Gillenwater# | 0 | 1940-1946 | |
| 50 | Sid Gordon# | 0 | 1941-1946 | |
| 50 | Joe Grace# | 0 | 1938-1946 | |
| 50 | Gene Hermanski# | 0 | 1943-1946 | |
| 50 | Ralph Hodgin# | 0 | 1939-1946 | |
| 50 | Ralph Kiner# | 0 | 1946-1946 | |
| 50 | Johnny Lazor# | 0 | 1943-1946 | |
| 50 | Johnny Lindell# | 0 | 1941-1946 | |
| 50 | Tom McBride# | 0 | 1943-1945 | |
| 50 | Dale Mitchell# | 0 | 1946-1946 | |
| 50 | Howie Moss# | 0 | 1942-1942 | |
| 50 | Johnny Ostrowski# | 0 | 1943-1945 | |
| 50 | Mel Ott# | 0 | 1926-1945 | |
| 50 | Dave Philley# | 0 | 1941-1946 | |
| 50 | Whitey Platt# | 0 | 1942-1946 | |
| 50 | Bama Rowell# | 0 | 1939-1946 | |
| 50 | Harry Walker# | 0 | 1940-1946 | |
| 50 | Taffy Wright# | 0 | 1938-1946 | |
| 50 | Johnny Wyrostek# | 0 | 1942-1946 |
