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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Red Ruffing# | 4258.0 | 1924-1946 | |
| 2 | Ted Lyons# | 4181.0 | 1923-1946 | |
| 3 | Bobo Newsom# | 3286.0 | 1929-1946 | |
| 4 | Mel Harder# | 3254.0 | 1928-1945 | |
| 5 | Bucky Walters# | 2867.0 | 1931-1946 | |
| 6 | Tommy Bridges# | 2809.0 | 1930-1946 | |
| 7 | Bill Lee# | 2754.0 | 1934-1946 | |
| 8 | Claude Passeau# | 2609.0 | 1935-1946 | |
| 9 | Hal Schumacher# | 2439.0 | 1931-1946 | |
| 10 | Curt Davis# | 2337.0 | 1934-1946 | |
| 11 | Thornton Lee# | 2244.0 | 1933-1946 | |
| 12 | Dutch Leonard# | 2229.0 | 1933-1946 | |
| 13 | Si Johnson# | 2038.0 | 1928-1943 | |
| 14 | Bill Dietrich# | 1917.0 | 1933-1946 | |
| 15 | Harry Gumbert# | 1770.0 | 1935-1944 | |
| 16 | Schoolboy Rowe# | 1757.0 | 1933-1946 | |
| 17 | Rip Sewell# | 1659.0 | 1932-1946 | |
| 18 | Mort Cooper# | 1626.0 | 1938-1946 | |
| 19 | Bob Feller# | 1625.0 | 1936-1946 | |
| 20 | Fritz Ostermueller# | 1618.0 | 1934-1946 | |
| 21 | Denny Galehouse# | 1573.0 | 1934-1946 | |
| 21 | Dizzy Trout# | 1573.0 | 1939-1946 | |
| 23 | Jack Knott# | 1550.0 | 1933-1942 | |
| 24 | Al Hollingsworth# | 1473.0 | 1935-1946 | |
| 25 | Jim Bagby# | 1444.0 | 1938-1945 | |
| 26 | Eddie Smith# | 1438.0 | 1936-1946 | |
| 27 | Hal Newhouser# | 1421.0 | 1939-1946 | |
| 28 | George Caster# | 1361.0 | 1934-1946 | |
| 29 | Johnny Vander Meer# | 1319.0 | 1937-1946 | |
| 30 | Nels Potter# | 1296.0 | 1936-1946 | |
| 31 | Kirby Higbe# | 1262.0 | 1937-1946 | |
| 32 | Johnny Niggeling# | 1233.0 | 1938-1946 | |
| 33 | Al Benton# | 1197.0 | 1934-1946 | |
| 34 | Spud Chandler# | 1193.0 | 1937-1946 | |
| 35 | Al Javery# | 1139.0 | 1940-1945 | |
| 36 | Tiny Bonham# | 1136.0 | 1940-1946 | |
| 37 | Johnny Rigney# | 1109.0 | 1937-1946 | |
| 38 | Hugh Mulcahy# | 1092.0 | 1935-1945 | |
| 39 | Max Lanier# | 1068.0 | 1938-1946 | |
| 40 | Mace Brown# | 1049.0 | 1935-1943 | |
| 41 | Clyde Shoun# | 1029.0 | 1935-1946 | |
| 42 | Hank Borowy# | 991.0 | 1942-1946 | |
| 43 | Bob Klinger# | 990.0 | 1938-1943 | |
| 44 | Bob Muncrief# | 989.0 | 1937-1946 | |
| 45 | Johnny Humphries# | 984.0 | 1938-1946 | |
| 46 | Al Milnar# | 981.0 | 1936-1943 | |
| 47 | Johnny Lanning# | 976.0 | 1936-1945 | |
| 48 | Johnny Murphy# | 945.0 | 1932-1943 | |
| 49 | Roger Wolff# | 941.0 | 1941-1946 | |
| 50 | Tex Hughson# | 915.0 | 1941-1946 | |
| 51 | Ed Heusser# | 911.0 | 1935-1946 | |
| 52 | Red Barrett# | 862.0 | 1937-1946 | |
| 53 | Jack Kramer# | 860.0 | 1939-1946 | |
| 54 | Steve Sundra# | 855.0 | 1936-1944 | |
| 55 | Joe Haynes# | 793.0 | 1939-1946 | |
| 56 | Mike Ryba# | 786.0 | 1935-1946 | |
| 57 | Early Wynn# | 779.0 | 1939-1946 | |
| 58 | Hank Wyse# | 771.0 | 1942-1946 | |
| 59 | Russ Christopher# | 764.0 | 1942-1946 | |
| 60 | Orval Grove# | 756.0 | 1940-1946 | |
| 61 | Sid Hudson# | 741.0 | 1940-1942 | |
| 62 | Joe Dobson# | 738.0 | 1939-1946 | |
| 63 | Harry Feldman# | 718.0 | 1941-1946 | |
| 63 | Nate Andrews# | 718.0 | 1937-1945 | |
| 65 | Hugh Casey# | 708.0 | 1935-1946 | |
| 66 | Mickey Haefner# | 702.0 | 1943-1946 | |
| 67 | Lum Harris# | 688.0 | 1941-1944 | |
| 68 | Jesse Flores# | 687.0 | 1942-1946 | |
| 69 | Bill Zuber# | 673.0 | 1936-1945 | |
| 70 | Marius Russo# | 662.0 | 1939-1943 | |
| 71 | Bill Posedel# | 651.0 | 1938-1941 | |
| 72 | Johnny Gorsica# | 642.0 | 1940-1944 | |
| 72 | Allie Reynolds# | 642.0 | 1942-1946 | |
| 74 | Nick Strincevich# | 637.0 | 1940-1946 | |
| 75 | Rube Melton# | 616.0 | 1941-1946 | |
| 76 | Bill Voiselle# | 610.0 | 1942-1946 | |
| 77 | Art Herring# | 601.0 | 1929-1945 | |
| 78 | Jake Wade# | 592.0 | 1936-1946 | |
| 79 | Steve Gromek# | 591.0 | 1941-1946 | |
| 80 | Junior Thompson# | 588.0 | 1939-1942 | |
| 81 | Russ Bauers# | 575.0 | 1936-1946 | |
| 82 | Stubby Overmire# | 570.0 | 1943-1946 | |
| 83 | Al Gerheauser# | 565.0 | 1943-1946 | |
| 83 | Harry Brecheen# | 565.0 | 1940-1946 | |
| 85 | Joe Krakauskas# | 563.0 | 1937-1946 | |
| 86 | Hal Gregg# | 553.0 | 1943-1946 | |
| 87 | Ace Adams# | 550.0 | 1941-1945 | |
| 88 | Ken Heintzelman# | 537.0 | 1937-1942 | |
| 88 | Phil Marchildon# | 537.0 | 1940-1946 | |
| 90 | Vern Olsen# | 520.0 | 1939-1946 | |
| 91 | Johnny Podgajny# | 516.0 | 1940-1946 | |
| 92 | Preacher Roe# | 514.0 | 1938-1946 | |
| 93 | Don Black# | 510.0 | 1943-1945 | |
| 94 | Walt Masterson# | 507.0 | 1939-1946 | |
| 95 | Ed Lopat# | 502.0 | 1944-1946 | |
| 96 | Paul Erickson# | 498.0 | 1941-1946 | |
| 97 | Charlie Wagner# | 497.0 | 1938-1942 | |
| 98 | Oscar Judd# | 495.0 | 1941-1946 | |
| 99 | Ken Raffensberger# | 493.0 | 1939-1946 | |
| 100 | Ike Pearson# | 491.0 | 1939-1942 |
